Enteroinvasive Escherichia coli for children

Enteroinvasive Escherichia coli for children

 Enteroinvasive Escherichia coli for children

. Ola Jamil JubeirAssistant Lecturer

       It is the strain that causes inflammation of the mucous and submucosal layer of the intestine, and it is a strain that is able to invade the colonic epithelial cells of the large intestine and spread from one cell to another, which causes inflammatory reactions that result in ulcers, which may sometimes cause dysentery (Nataro and kaper, 1998). Among the symptoms caused by this strain are severe abdominal cramps, malaise, watery stools, tenesmus and fever, and 10% of cases develop into liquid stools that contain blood and mucus frequently and little and contain a quantity of white blood cells. Symptoms of the disease appear 18 hours after eating food. Contaminant, these pathogenic bacteria are closely related to ETEC, there are a few biochemical characteristics that can be used to distinguish between ETEC and EIEC as 70% of EIEC isolates are not lactose-fermenting, in addition to their inability to hydrolyze carboxylates (Silva et al., 1980).

EIEC causes colitis and inflammatory dysentery with clinical symptoms (blood, mucus, stool accompanied by fever and severe cramps) (Welch, 2006). Several genes that encode for virulence factors that aid in cell invasion and cause various seizures are found on a large plasmid <200kb) in EIEC, and interestingly, their inability to produce DE-carboxylate lysine is a common trait between EIEC and ETEC which is the result of mutations and gene rearrangements. in the cad C gene (Casalino et al., 2003).

Plasmids carry an important type III secretion gene system that receives signals from the host cell for membrane analysis. A role in the spread of bacterial cells to other host cells (Welch, 2006).

This group possesses many serotypes that have a high ability to adhere to the epithelial cells of the intestine and possess high levels of toxins, the most important of which are O28ac, O29, O124, O136, O143, O144, O152, O164, O167, O86, O119, O127 (Nataro and Kaper, 1998).

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