البحوث العلمية

البحوث المنشورة

ORIGINAL RESEARCH ARTICLES

ZGAIR, A., WONG, J. C., SABRI, A., FISCHER, P. M., BARRETT, D. A., CONSTANTINESCU, C. S. & GERSHKOVICH, P. 2015. Development of a simple and sensitive HPLC–UV method for the simultaneous determination of cannabidiol and Δ9-tetrahydrocannabinol in rat plasma. Journal of pharmaceutical and biomedical analysis, 114, 145-151.

ZGAIR, A., WONG, J. C., LEE, J. B., MISTRY, J., SIVAK, O., WASAN, K. M., HENNIG, I. M., BARRETT, D. A., CONSTANTINESCU, C. S. & FISCHER, P. M. 2016. Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines. American journal of translational research, 8, 3448.

ZGAIR, A., LEE, J. B., WONG, J. C., TAHA, D. A., ARAM, J., DI VIRGILIO, D., MCARTHUR, J. W., CHENG, Y.-K., HENNIG, I. M. & BARRETT, D. A. 2017. Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation. Sci Rep, 7, 14542.

TAHA, D. A., ZGAIR, A., LEE, J. B., DE MOOR, C. H., BARRETT, D. A., BRUCE, K. D., SUNGELO, M., ECKEL, R. H. & GERSHKOVICH, P. 2017. Hyperlipidaemia alone and in combination with acidosis can increase the incidence and severity of statin-induced myotoxicity. European Journal of Pharmaceutical Sciences, 100, 163-175.

LEE, J. B., ZGAIR, A., KIM, T. H., KIM, M. G., YOO, S. D., FISCHER, P. M. & GERSHKOVICH, P. 2017. Simple and sensitive HPLC-UV method for determination of bexarotene in rat plasma. Journal of Chromatography B, 1040, 73-80.

LEE, J. B., ZGAIR, A., TAHA, D. A., ZANG, X., KAGAN, L., KIM, T. H., KIM, M. G., YUN, H.-Y., FISCHER, P. M. & GERSHKOVICH, P. 2017. Quantitative analysis of lab-to-lab variability in Caco-2 permeability assays. European Journal of Pharmaceutics and Biopharmaceutics, 114, 38-42.

NOMAN, J. A., LAFI, M. A. & ZGAIR, A. K. 2012. Effect of Tramadol on Ovine Ureteral Smooth Muscle Contractility: an in vitro Experimental Study.  Anbar Medical Journal

LEE, J. B., ZGAIR, A., MALEC, J., KIM, T. H., KIM, M. G., ALI, J., ... & VORONIN, G. 2018. Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system. Journal of controlled release, 286, 10-19.

ALI, J., ZGAIR, A., HAMEED, G. S., GARNETT, M. C., ROBERTS, C. J., BURLEY, J. C., & GERSHKOVICH, P. 2019. Application of biorelevant saliva-based dissolution for optimisation of orally disintegrating formulations of felodipine. International journal of pharmaceutics, 555, 228-236.

LEE, J. B., KIM, T. H., FENG, W., CHOI, H. G., ZGAIR, A., SHIN, S., ... & SHIN, B. S. 2019. Quantitative Prediction of Oral Bioavailability of a Lipophilic Antineoplastic Drug Bexarotene Administered in Lipidic Formulation Using a Combined In Vitro Lipolysis/Microsomal Metabolism Approach. Journal of pharmaceutical sciences, 108(2), 1047-1052.

LEE, J. B., RADHI, M., CIPOLLA, E., GANDHI, R. D., SARMAD, S., ZGAIR, A., ... & ORTORI, C. A. 2019. A novel nucleoside rescue metabolic pathway may be responsible for therapeutic effect of orally administered cordycepin. Scientific reports, 9(1), 1-12.

ZGAIR A, DAWOOD Y, IBRAHEM SM, BACK HM, KAGAN L, GERSHKOVICH P, LEE JB. Predicting Intestinal and Hepatic First-Pass Metabolism of Orally Administered Testosterone Undecanoate. Applied Sciences. 2020 Jan;10(20):7283.

QIN C, CHU Y, FENG W, FROMONT C, HE S, ALI J, LEE JB, ZGAIR A, BERTON M, BETTONTE S, LIU R. Targeted delivery of lopinavir to HIV reservoirs in the mesenteric lymphatic system by lipophilic ester prodrug approach. Journal of Controlled Release. 2021 Jan 10;329:1077-89.

ZGAIR A, DAWOOD Y, IBRAHEM SM, LEE JB, FENG W, FISCHER PM, GERSHKOVICH P. Strawberry Decreases Intraluminal and Intestinal Wall Hydrolysis of Testosterone Undecanoate. Molecules. 2021 Jan;26(1):233.

FENG W, QIN C, CHU Y, BERTON M, LEE JB, ZGAIR A, BETTONTE S, STOCKS MJ, CONSTANTINESCU CS, BARRETT DA, FISCHER PM. Natural sesame oil is superior to pre-digested lipid formulations and purified triglycerides in promoting the intestinal lymphatic transport and systemic bioavailability of cannabidiol. European Journal of Pharmaceutics and Biopharmaceutics. 2021 May 1;162:43-9.

RASHID RA, ZGAIR A, AL-ANI RM. Effect of nasal corticosteroid in the treatment of anosmia due to COVID-19: A randomised double-blind placebo-controlled study. American Journal of Otolaryngology. 2021 Sep 1;42(5):103033.

LEE JB, ZANG X, ZGAIR A, OOI TQ, FOLEY DW, VORONIN G, KAGAN L, SOUKARIEH F, GAO R, SHAO H, SOH WT. Postprandial administration but not controlled release in the colon increases oral bioavailability of DF030263, a promising drug candidate for chronic lymphocytic leukemia. European Journal of Pharmaceutics and Biopharmaceutics. 2021 May 12.

BOOK CHAPTER

ZGAIR, A., WONG, J. C. M. & GERSHKOVICH, P. 2016b. Targeting Immunomodulatory Agents to the Gut-Associated Lymphoid Tissue. Neuro-Immuno-Gastroenterology. Springer, Cham.

المحاضرات العلمية

السلسل	المادة	اسم المحاضرة	المرحلة	التحميل	مشاهدة
1	Therapeutic drug monitoring	Introduction to PK and PD	الخامسة
2	Therapeutic drug monitoring	PK in special populations	الخامسة
3	Therapeutic drug monitoring	Practice problems	الخامسة
4	Therapeutic drug monitoring	PK modelling continue	الخامسة
5	Therapeutic drug monitoring	Pharmacokinetic modelling	الخامسة

الشهادات الاكاديمية

·       بكالوريوس علوم صيدلانية – كلية الصيدلة – جامعة بغداد – العراق  2002

·       ماجستير ادوية – كلية الطب - جامعة الانبار - العراق 2010

·       دكتوراه صيدلة/ حركية الدواء – الصيدلة – جامعة نوتنجهام – المملكة المتحدة 2017

الاشراف

الاشراف على بحث التخرج لطلبة المرحلة الخامسة للعام الدراسي 2017-2018   ثلاث طلاب

الاشراف على بحث التخرج لطلبة المرحلة الخامسة للعام الدراسي 2018-2019   ثلاث طلاب

الاشراف على بحث التخرج لطلبة المرحلة الخامسة للعام الدراسي 2019-2020   اربع طلاب

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