The public discussion of the master’s student (Rafal Sa'ad Enad), Department of Biology - College of Science - University of Anbar, took place on Tuesday, 20/9/2022 in Jaber bin Hayyan Hall in the College of Science about her thesis tagged: -

Association of TLR2 and TLR4 Gene Polymorphism with Type and SEVERITY of otitis media bacterial infection

The study aimed to distribution of different bacterial pathogens in Otitis media (OM) infections in Ramadi city and Study of the most frequent bacteria, bacterial sensitivity, and biofilm formation efficiency among different infections and Assessment of the relationships between different genotypes in TLR2 and TLR4 with type and severity of bacterial infection.

The study showed that most bacteria isolated from (OM) are Gram-Negative Bacteria. The antibiotic susceptibility test shows that all isolates were 100% susceptible to Imipenem, whereas Ampicillin and Ceftriaxone were the least effective. Pseudomonas aeruginosa and Staphylococcus spp., show biofilm-forming potential in all samples This study extended the evaluation of TLR2 and TLR4’s role in the etiology of OM, as some SNPs (TLR2 gene: rs5743708; TLR4 gene: rs4986790 and rs4986791) were significantly associated with susceptibility to this OM.